10 Best Ant Sprays 2026 in the United States

The Ortho Home Defense Insect Killer is a large 1.33-gallon spray designed for both indoor and outdoor use, especially around home entry points like doors, windows, patios, and foundations. Its active ingredient is bifenthrin at 0.05%, a common and effective chemical for killing ants, cockroaches, spiders, and many other pests. It offers long-lasting protection for up to 12 months on indoor non-porous surfaces, helping prevent repeat infestations without frequent reapplication.

The Hot Shot Fogger With Odor Neutralizer is designed to kill ants, roaches, spiders, and fleas on contact and continues to work for up to two months. This fogger is effective for heavy infestations and can penetrate deep into cracks and crevices to reach hidden bugs. The active ingredients, Tetramethrin and Cypermethrin, are potent insecticides known for their effectiveness.

The Ortho Home Defense Max Indoor Insect Barrier is a convenient ready-to-use spray designed to kill ants and a variety of other common household pests like roaches, spiders, fleas, and ticks. It contains 0.05% bifenthrin as its active ingredient, which is known for effective pest control with a lasting barrier effect. One of its biggest advantages is its long residual protection—up to 365 days on nonporous indoor surfaces—helping keep your home pest-free for a full year after application.